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Plasmodium falciparum Gametocyte Culture and Mosquito Infection Through Artificial Membrane Feeding
Published on: July 3, 2020
Still enigmatic: Plasmodium oocysts 125 years after their discovery
Franziska Hentzschel1, Friedrich Frischknecht1
1Integrative Parasitology, Center for Infectious Diseases, Heidelberg University Medical School, Im Neuenheimer Feld 344, 69120 Heidelberg, Germany; German Center for Infection Research, TTU Malaria and Neglected Tropical Diseases, partner site Heidelberg, Germany.
Abstract:
One hundred and twenty five years ago, in August 1897, Ronald Ross discovered forms of the malaria parasite in the gut of two mosquitoes. Shortly afterwards, Giovanni Battista Grassi established how the transmissive forms of the parasite, sporozoites, develop in these Plasmodium oocysts. Today, we still understand surprisingly little about the molecular processes governing oocyst biology.
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