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Selective detection of HSO3- in living cells using a pyrroloquinoline structure containing turn-on fluorescent probe
Jiahua Zhou1, Fa Wang1, Yuan-Xiang Xu1
1School of Chemistry and Chemical Engineering, Nantong University, Nantong, 226019, China.
Abstract:
A turn-on fluorescence probe PQP-1 with a pyrroloquinoline skeleton has been designed and synthesized. Probe PQP-1 showed high sensitivity to HSO3-, low detection limit (16.83 nM), and a wide linear range (50-3000 μM). More importantly, probe PQP-1 could distinguish between HSO3- and SO32-. Furthermore, cell imaging experiments of HSO3- in HeLa cells revealed that probe PQP-1 had potential application value in biological systems.
