Stem cells and common biomaterials in dentistry: a review study

Area of Science:

• Regenerative Medicine
• Biomaterials Science
• Oral and Maxillofacial Surgery

Background:

• Stem cells possess self-renewal and differentiation capabilities, crucial for tissue repair.
• Intra- and extra-oral tissues are identified as accessible reservoirs for stem cells.
• The potential of stem cells in clinical fields, drug discovery, and scientific research is significant.

Purpose of the Study:

• To review the essential components of tissue engineering in dentistry.
• To examine stem cells from intra- and extra-oral sources.
• To discuss the role of growth factors and scaffolds in dental applications.

Main Methods:

• Literature review of stem cell sources, growth factors, and scaffolds in dentistry.
• Analysis of current research trends in oral tissue engineering.
• Synthesis of information on clinical applications and future directions.

Main Results:

• Intra- and extra-oral stem cells represent a promising, accessible source for regenerative therapies.
• Growth factors and biocompatible scaffolds are critical for successful tissue regeneration.
• Tissue engineering holds significant potential for advancing dental treatments.

Conclusions:

• Stem cell-based therapies, utilizing accessible oral sources, are poised to revolutionize dentistry.
• The integration of stem cells, growth factors, and scaffolds is key to effective tissue engineering.
• Further research is warranted to optimize these components for widespread clinical use.