Related Experiment Video
Updated: Sep 7, 2025

05:06
Author Spotlight: Advancements in Nanoparticle Technology for Drug Delivery and Immunotherapy
Published on: November 10, 2023
1.1K
Recent advances in pain management based on nanoparticle technologies.
Soraya Babaie1, Arezou Taghvimi2, Joo-Hyun Hong3
1Physical Medicine and Rehabilitation Research Center and Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Journal of Nanobiotechnology
|June 18, 2022
Summary
Nanotechnology offers promising advancements in pain management by improving drug delivery and diagnostics. Further research is needed to fully realize its potential in controlling acute and chronic pain effectively.
Area of Science:
- Biomedical Engineering
- Materials Science
- Pharmacology
Background:
- Pain is a critical sensory signal indicating potential injury.
- Effective pain management is central to medical treatment.
- Nanotechnology has shown significant progress in pain management applications.
Purpose of the Study:
- To review the literature on nanotechnology applications in pain management.
- To explore the use of nanotechnology in acute and chronic pain control.
Main Methods:
- Systematic literature review of 227 articles up to April 2021.
- Data collection from Web of Science, PubMed, Scopus, and Google Scholar.
Main Results:
- Nanotechnology-based drug delivery enhances analgesic efficacy and reduces side effects.
- Nanosystems improve disease imaging and diagnostics for faster pain-related condition diagnosis.
- Nanotechnology enables accurate pain measurement for evaluating intervention effectiveness.
Conclusions:
- Nanotechnology is revolutionizing pain management with promising outcomes.
- Further extensive research is required to establish nanotechnology's full clinical impact.
- Continued investigation is crucial for advancing nanotechnology in pain management.
Related Concept Videos
Analgesia and Pain Management
788
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
788
Opioid Analgesics: Synthetic and Semisynthetic Opioids
417
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
417
Nociception
29.4K
Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain.
29.4K

