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Updated: Sep 7, 2025

Laparoscopic-Assisted Seldinger Technique for Peritoneal Dialysis Catheter Insertion
Published on: May 23, 2025
Deeper may not be better: relationship between catheter dysfunction and location of the catheter tip in right-sided
N Y T Soh1, B S Tan1, S J M Chan1
1Department of Vascular and Interventional Radiology, Singapore General Hospital, Singapore.
Insights
Optimal placement of tunnelled central venous catheters (CVCs) in the superior vena cava (SVC) reduces catheter dysfunction in haemodialysis patients. This finding is crucial for improving CVC longevity and patient outcomes.
Area of Science:
- Nephrology
- Vascular Surgery
- Radiology
Background:
- Tunnelled central venous catheters (CVCs) are essential for haemodialysis access.
- Catheter dysfunction is a common complication, impacting treatment efficacy.
- Optimal catheter tip positioning is hypothesized to influence CVC function.
Purpose of the Study:
- To investigate the association between the tip location of tunnelled CVCs and the incidence of catheter dysfunction.
- To identify ideal catheter tip placement for reducing complications in haemodialysis patients.
Main Methods:
- Retrospective analysis of 993 haemodialysis patients with tunnelled CVCs (step-tip design) inserted via the right internal jugular vein.
- Categorization of catheter tip position into superior vena cava (SVC), cavo-atrial junction (CAJ), or deep right atrium (DRA) using intra-procedural radiographs.
- Tracking of patients for 90 days post-insertion to record complications requiring catheter replacement.
Main Results:
- Catheter dysfunction necessitating replacement occurred in 9.6% of patients within 90 days.
- SVC tip location was associated with significantly lower dysfunction rates (1.9%) compared to CAJ (8%) and DRA (11%; p=0.049).
- No significant relationship was found between tip location and other complications like infection or dislodgement.
Conclusions:
- Positioning the catheter tip in the SVC is linked to a reduced risk of dysfunction for tunnelled CVCs with a step-tip design.
- This finding supports SVC as the preferred location to minimize catheter-related issues in haemodialysis patients.
Aim:
To examine the relationship between catheter tip location and catheter dysfunction in the context of tunnelled central venous catheters (CVCs) for haemodialysis.
Materials And Methods:
This was a retrospective study of 993 haemodialysis patients who underwent insertion of tunnelled CVCs of step-tip design via the right internal jugular vein (IJV). Based on intra-procedural radiographs, the catheter tip was characterised as being in the superior vena cava (SVC), cavo-atrial junction (CAJ), or deep right atrium (DRA). Patients were tracked for 90 days post-procedure for complications resulting in catheter replacement, and these were compared between cohorts. Statistical analysis was performed with Pearson's chi-square and Fisher's exact tests for categorical variables and two-sample t-test and one-way analysis of variance (ANOVA) for continuous variables.
Results:
Ninety-five patients (9.6%) experienced catheter dysfunction necessitating replacement within 90 days of insertion. Tip location in SVC was associated with lower occurrence of catheter dysfunction (1.9%) as compared with the CAJ (8%) and DRA (11%; p=0.049). Catheter replacement due to other complications (catheter-associated bacteraemia, cuff dislodgement, exit-site infection, external catheter damage) showed no statistically significant relation to location of the CVC tip.
Conclusion:
When utilising tunnelled CVCs with a step-tip design inserted via the right IJV, location of the catheter tip in the SVC is associated with reduced occurrence of catheter dysfunction as compared to either the CAJ or DRA.
Related Concept Videos
Hemodialysis I: Introduction
Cardiac Catheterization I: Pre-Procedure Overview
Cardiac Catheterization II: Right Heart Catheterization
Hemodialysis II: Procedure and Complications
Cardiac Catheterization III: Left Heart Catheterization
Cardiac Catheterization IV: Nursing Management

