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Updated: Sep 7, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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An unprecedented ergostane with a 6/6/5 tricyclic 13(14 → 8)abeo-8,14-seco skeleton from Talaromyces adpressus

Mi Zhang1, Qin Li2, Shuangjun Li3

  • 1Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Department of In Vitro Diagnostic Reagent, National Institutes for Food and Drug Control (NIFDC), Beijing 100050, China.

Bioorganic Chemistry
|June 19, 2022
PubMed

Keywords:
Anti-inflammatory activityDankasteroneNF-κB pathwayRearranged steroidTalaromyces adpressus

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