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Updated: Sep 7, 2025

Utilizing the Modified T-Maze to Assess Functional Memory Outcomes After Cardiac Arrest
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Long Term Cognitive Function After Cardiac Arrest: A Mini-Review.

Guri Hagberg1,2, Håkon Ihle-Hansen1,3, Else Charlotte Sandset2

  • 1Department of Medical Research, Baerum Hospital Vestre Viken Hospital Trust, Drammen, Norway.

Frontiers in Aging Neuroscience
|June 20, 2022
PubMed
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Survival from out-of-hospital cardiac arrest is increasing, but cognitive impairments due to hypoxic brain injury are a concern. Routine cognitive screening for survivors is lacking, highlighting a need for standardized assessment methods.

Area of Science:

  • Cardiology
  • Neurology
  • Emergency Medicine

Background:

  • Out-of-hospital cardiac arrest (OHCA) remains a significant global cause of death.
  • Improved resuscitation techniques and public access to defibrillators have increased OHCA survival rates.
  • Survivors face risks of hypoxic brain injury and subsequent cognitive deficits.

Purpose of the Study:

  • To review existing evidence on hypoxic brain injury and long-term cognitive function in OHCA survivors.
  • To identify gaps in knowledge regarding cognitive assessment and screening in this population.

Main Methods:

  • Narrative mini-review of available scientific literature.
  • Exploration of studies focusing on cardiac arrest, resuscitation, and neurological outcomes.
Keywords:
cardiac arrestcognitioncognitive impaimentdementiahypoxic brain injury

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Main Results:

  • Increased survival from OHCA is documented.
  • Cognitive function is not consistently assessed post-resuscitation.
  • A lack of consensus exists on appropriate screening tools for cognitive impairment in survivors.

Conclusions:

  • While OHCA survival is improving, long-term cognitive sequelae require further investigation.
  • Standardized cognitive screening protocols are needed for OHCA survivors.
  • Further research is essential to address knowledge deficits in managing post-cardiac arrest cognitive dysfunction.