Related Experiment Video
Updated: Sep 7, 2025

Exploring Arterial Smooth Muscle Kv7 Potassium Channel Function using Patch Clamp Electrophysiology and Pressure Myography
Published on: September 14, 2012
Hydrogen Sulfide-Induced Vasodilation: The Involvement of Vascular Potassium Channels
Xiao-Yu Liu1, Ling-Ling Qian1, Ru-Xing Wang1
1Department of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Abstract:
Hydrogen sulfide (H2S) has been highlighted as an important gasotransmitter in mammals. A growing number of studies have indicated that H2S plays a key role in the pathophysiology of vascular diseases and physiological vascular homeostasis. Alteration in H2S biogenesis has been reported in a variety of vascular diseases and H2S supplementation exerts effects of vasodilation. Accumulating evidence has shown vascular potassium channels activation is involved in H2S-induced vasodilation. This review aimed to summarize and discuss the role of H2S in the regulation of vascular tone, especially by interaction with different vascular potassium channels and the underlying mechanisms.
More Related Videos
Related Concept Videos
Antihypertensive Drugs: Vasodilators
Antihypertensive Drugs: Potassium-Sparing Diuretics
Vascular Spasm
Nitric Oxide Signaling Pathway
Antihypertensive Drugs: Action of Calcium Channel Blockers
Mechanically-gated Ion Channels

