Related Experiment Video

Updated: Sep 7, 2025

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
05:16

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

211

Gout increases length of stay in patients hospitalized for heart failure exacerbation

Daniel DeMizio1, Guojing Wu2, Ying Wei2

  • 1Division of Rheumatology, Columbia University Irving Medical Center, 630 West 168th Street, Suite 3-450, New York, NY 10032, USA.

Therapeutic Advances in Musculoskeletal Disease
|June 20, 2022
PubMed

Insights

Patients with gout history admitted for heart failure exacerbation experienced longer hospital stays. A gout flare during hospitalization significantly increased the length of stay compared to those without gout.

Area of Science:

  • Cardiology
  • Rheumatology
  • Health Services Research

Background:

  • Gout is a common comorbidity that may impact hospital outcomes.
  • The effect of gout on length of stay (LoS) for heart failure (HF) exacerbations is not well understood.
  • This study investigates if gout diagnosis or a gout flare during hospitalization prolongs LoS in HF patients.

Purpose of the Study:

  • To determine the impact of gout on hospital LoS in patients admitted for heart failure exacerbation.
  • To differentiate the effect of a gout diagnosis versus an active gout flare on LoS.
  • To provide data for optimizing care pathways for HF patients with gout.

Main Methods:

  • A matched retrospective cohort study design was employed.
  • Electronic medical records of HF patients admitted between July 2012 and June 2017 were analyzed.
  • Patients with gout were matched to controls without gout, and those experiencing a gout flare were specifically identified. Linear mixed-effect models were used to compare log-transformed LoS.

Main Results:

  • A total of 978 admissions (738 patients) were analyzed, including 246 with gout and 492 controls.
  • Patients with gout had a significantly longer log LoS (1.86 ± 0.95) compared to controls (1.72 ± 0.94; p=0.0278).
  • Gout flares during admission were associated with a substantially longer log LoS (2.41 ± 0.96) compared to non-gout patients (p<0.0001), and also longer than gout patients without flares (p=0.042).

Conclusions:

  • Heart failure patients with a history of gout experience significantly longer hospitalizations.
  • The primary driver for increased LoS in gout patients admitted for HF exacerbation is the occurrence of a gout flare during the hospital stay.
  • These findings highlight the importance of managing gout flares in hospitalized HF patients to potentially reduce length of stay.
Abstract

Keywords:
gouthealthcareheart failure

More Related Videos

Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis04:05

Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis

Published on: June 30, 2023

2.2K
Author Spotlight: Workflow for Integrating POCUS Data into EHR for Managing Heart Failure Patients03:47

Author Spotlight: Workflow for Integrating POCUS Data into EHR for Managing Heart Failure Patients

Published on: July 12, 2024

870

Related Concept Videos

Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
26
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
23
Heart Failure VII: Nursing Interventions01:30

Heart Failure VII: Nursing Interventions

The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
137
Mitral Regurgitation IV: Nursing Management01:28

Mitral Regurgitation IV: Nursing Management

Mitral regurgitation (MR) is a condition where the mitral valve does not close properly, leading to the backward flow of blood from the left ventricle into the left atrium during systole. This condition can arise from various causes, including rheumatic fever, infective endocarditis, or degenerative valve disease. Effective nursing management is crucial to optimizing patient outcomes and involves comprehensive assessment and targeted interventions.Comprehensive Patient AssessmentA detailed...
80
Heart Failure Drugs: Diuretics01:22

Heart Failure Drugs: Diuretics

Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
479
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
41