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Hypertension in Women

Tatjana Tasić1, Marijana Tadić2, Maja Lozić3

  • 1School of Dental Medicine, University of Belgrade, Belgrade, Serbia.

Frontiers in Cardiovascular Medicine
|June 20, 2022
PubMed

Insights

Hypertension in women involves complex mechanisms influenced by life stages and physiological factors. Understanding these unique pathways is key to effective treatment strategies for female hypertension.

Area of Science:

  • Cardiovascular Science
  • Women's Health
  • Hypertension Research

Background:

  • Hypertension is a leading cause of morbidity and mortality globally.
  • The specific pathophysiological mechanisms of hypertension in women remain incompletely understood.
  • Female physiology presents unique challenges in hypertension development and treatment across different life stages.

Purpose of the Study:

  • To summarize current knowledge on the mechanisms of hypertension in women.
  • To review established and emerging treatment strategies for hypertension in females.
  • To highlight the influence of female-specific physiological factors on blood pressure regulation.

Main Methods:

  • Literature review of clinical and experimental findings.
  • Analysis of studies focusing on sex hormones, autonomic nervous system, renin-angiotensin-aldosterone system, and arterial stiffness.
  • Synthesis of data across different female life stages from youth to senescence.

Main Results:

  • Sex hormones significantly impact blood pressure regulation in women.
  • The autonomic nervous system and renin-angiotensin-aldosterone system play crucial roles.
  • Increased arterial stiffness contributes to hypertension development in females.
  • Hypertension mechanisms and treatment considerations vary across the female lifespan.

Conclusions:

  • Understanding the unique mechanisms of hypertension in women is critical.
  • Tailored treatment approaches considering female physiology are necessary.
  • Further research is needed to fully elucidate and manage hypertension in women throughout their lives.

Keywords:
antihypertensive treatmentpostmenopausal hypertensionpregnancy induced hypertensionsex differencessex hormones

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