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Unilateral Lung Volume Analysis Using Micro-CT for Enhanced Assessment of Pulmonary Fibrosis in Preclinical Models
Published on: June 20, 2025
Post-Coronavirus Disease 2019 Pulmonary Fibrosis: Wait or Needs Intervention
1Division of Allergy and Respiratory Diseases, Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea.
Pulmonary fibrosis is an increasing complication of COVID-19. This review explores its epidemiology, risk factors, pathogenesis, and management, highlighting the need for clearer definitions and evaluation timelines for this lung scarring condition.
Area of Science:
- Pulmonology
- Infectious Diseases
- Pathology
Background:
- Coronavirus disease 2019 (COVID-19) presents a significant global health challenge.
- While acute management is established, long-term complications like pulmonary fibrosis are increasingly recognized.
- Limited data and consensus exist regarding the definition and evaluation of post-COVID-19 pulmonary fibrosis.
Purpose of the Study:
- To review the current understanding of post-COVID-19 pulmonary fibrosis.
- To investigate its epidemiology, risk factors, and pathogenesis.
- To discuss current and potential management strategies.
Main Methods:
- Literature review of studies on post-COVID-19 pulmonary fibrosis.
- Analysis of epidemiological data, risk factors, and proposed pathogenetic mechanisms.
- Synthesis of information on clinical course and management approaches.
Main Results:
- Pulmonary fibrosis is a common respiratory complication of COVID-19, with increasing prevalence.
- Lesions often show improvement within a year, complicating timely evaluation.
- There is a lack of standardized criteria for defining and assessing this condition.
Conclusions:
- Post-COVID-19 pulmonary fibrosis requires further investigation due to its rising incidence.
- Standardized definitions and evaluation protocols are crucial for accurate diagnosis and management.
- Understanding risk factors and pathogenesis is key to developing effective treatments.
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