Long-COVID, Metabolic and Endocrine Disease

Related Experiment Video

Updated: Sep 7, 2025

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
10:03

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

Published on: February 28, 2013

25.9K

Stefan R Bornstein1,2, Diana Cozma1, Margrit Kamel3

  • 1Department of Medicine III, Universitätsklinikum Carl Gustav Carus, Dresden, Germany.

Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme
|June 20, 2022
PubMed

Insights

Long-COVID, a post-acute COVID-19 syndrome, affects up to 40% of infected individuals, causing chronic fatigue and cognitive issues. Management includes rehabilitation, diet, and potentially apheresis for symptom improvement.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Endocrinology

Background:

  • Long-COVID (post-acute COVID-19 syndrome) remains a significant global health challenge post-pandemic.
  • Up to 40% of SARS-CoV-2 infected individuals experience persistent, clinically relevant symptoms weeks to months after acute infection.
  • Key symptoms include chronic fatigue, dyspnea, and cognitive dysfunction, impacting quality of life.

Purpose of the Study:

  • To highlight the ongoing challenge of long-COVID and its impact.
  • To identify risk factors and potential long-term complications.
  • To emphasize the importance of structured management strategies for affected individuals.

Main Methods:

  • Review of current studies on long-COVID prevalence and symptoms.
  • Identification of risk factors such as overweight and diabetes mellitus.
  • Discussion of potential therapeutic interventions including rehabilitation, diet, and apheresis.

Main Results:

  • Overweight and diabetes mellitus are associated with an increased risk of long-COVID symptoms.
  • Steroid treatments for acute and long-COVID may lead to metabolic and endocrine disorders.
  • Structured rehabilitation, physical activity, and dietary management are crucial.

Conclusions:

  • Long-COVID presents a substantial and ongoing health burden requiring comprehensive management.
  • Integrated rehabilitation, lifestyle interventions, and targeted therapies like apheresis show promise for symptom amelioration.
  • Addressing metabolic and endocrine complications is vital for long-COVID patient care.

More Related Videos

An Advanced Murine Model for Nonalcoholic Steatohepatitis in Association with Type 2 Diabetes10:17

An Advanced Murine Model for Nonalcoholic Steatohepatitis in Association with Type 2 Diabetes

Published on: April 26, 2019

7.1K
Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT08:13

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT

Published on: January 7, 2018

69.3K

Related Concept Videos

Overview of Carbohydrate Metabolism01:19

Overview of Carbohydrate Metabolism

Carbohydrate metabolism is a fundamental biochemical process that ensures a constant supply of energy to living cells. The most important carbohydrate is glucose, which can be broken down via glycolysis to enter into the Krebs cycle and eventually lead to the production of ATP through oxidative phosphorylation.
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
1.7K
Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
2.3K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
1.2K
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
61
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
54
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
609