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Menopause, skin and common dermatoses. Part 2: skin disorders
Erin Kamp1, Mariha Ashraf1, Esra Musbahi1
1Department of Dermatology, University Hospitals Sussex NHS Foundation Trust, Brighton, UK.
Clinical and Experimental Dermatology
|June 21, 2022
Summary
Menopause significantly impacts skin structure and function, affecting conditions like xerosis and psoriasis due to reduced estrogen. Further research is needed to explore therapeutic options for menopausal skin changes.
Area of Science:
- Dermatology
- Endocrinology
- Women's Health
Background:
- Menopause is characterized by a hypo-oestrogenic state, significantly altering skin physiology.
- Estrogen plays a crucial role in maintaining skin hydration, collagen levels, and overall skin health.
- The decline in estrogen during menopause affects the skin's structure and functional integrity.
Purpose of the Study:
- To review the existing literature on the effects of menopause on the skin.
- To investigate the impact of menopausal hormonal changes on common dermatological conditions.
- To identify the relationship between menopause and specific skin disorders.
Main Methods:
- A comprehensive literature review was conducted.
- Searched databases for studies examining menopause and dermatoses.
- Synthesized findings on estrogen's role in skin health and disease.
Main Results:
- Estrogen deficiency is linked to increased transepidermal water loss and reduced dermal collagen.
- Menopause is associated with common dermatoses such as xerosis (dry skin) and pruritus (itching).
- Associations were found between menopause and conditions including hidradenitis suppurativa and psoriasis.
Conclusions:
- Menopause exerts a clear and significant impact on the skin and prevalent dermatological conditions.
- Understanding the mechanisms underlying menopausal skin changes is crucial.
- Further research is warranted to develop effective therapeutic strategies for menopausal skin issues.
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