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Updated: Sep 7, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
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[Critical coronavirus disease 2019 caused by Delta variant: a case report with literature review]

Yuzhan Liu1, Weifeng Xie2, Hui Li2

  • 1Department of Pulmonary and Critical Care Medicine, Qingdao Municipal Hospital, Qingdao 266011, Shandong, China.

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
|June 21, 2022
PubMed

Insights

Convalescent plasma (CP) therapy demonstrated significant effectiveness in treating a severe case of COVID-19 caused by the Delta variant. This approach holds considerable value for managing critical coronavirus disease 2019 patients.

Area of Science:

  • Virology
  • Immunology
  • Infectious Diseases

Background:

  • Severe and critical cases of COVID-19 caused by the Delta variant pose significant clinical challenges.
  • Investigating novel therapeutic strategies is crucial for improving patient outcomes.

Observation:

  • A 50-year-old unvaccinated male, diagnosed with critical COVID-19 post-Delta variant infection, presented with severe respiratory and gastrointestinal symptoms.
  • The patient's condition rapidly deteriorated despite standard medical care.

Findings:

  • Intravenous administration of convalescent plasma (CP) from Delta variant recovered patients was initiated on the sixth day of severe illness.
  • The patient exhibited rapid clinical improvement following CP therapy.

Implications:

  • Convalescent plasma therapy shows promising curative efficacy and significant clinical application value for severe and critical COVID-19.
  • This case highlights the potential of CP as a vital treatment option against Delta variant-induced coronavirus disease 2019.
Abstract

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