Persistent Dissociation and Its Neural Correlates in Predicting Outcomes After Trauma Exposure

Lauren A M Lebois¹, Nathaniel G Harnett¹, Sanne J H van Rooij¹+53

• ¹Division of Depression and Anxiety Disorders (Lebois, Harnett, Ravichandran, Dumornay, Finegold, Merker, Pizzagalli, Ressler), Institute for Technology in Psychiatry (Germine, Rauch), and Department of Psychiatry (Rauch), McLean Hospital, Belmont, Mass.; Department of Psychiatry (Lebois, Harnett, Ravichandran, Germine, Rauch, Pizzagalli, Ressler), Department of Emergency Medicine (Sanchez), and Department of Health Care Policy (Kessler), Harvard Medical School, Boston; Department of Psychiatry and Behavioral Sciences (van Rooij, Ely, Stevens), Department of Biomedical Informatics (Clifford), and Department of Emergency Medicine (Hudak), Emory University School of Medicine, Atlanta; Department of Psychiatry and Behavioral Neurosciences (Jovanovic) and Department of Emergency Medicine (Pearson, O'Neil), Wayne State University, Detroit; Department of Psychological Sciences, University of Missouri-St. Louis, St. Louis (Bruce); Department of Emergency Medicine, Washington University School of Medicine, St. Louis (House); Department of Psychology, Northern Illinois University, DeKalb (Hill); McLean Hospital, Belmont, Mass. (Phillips); Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore (Phillips); Department of Emergency Medicine and Department of Health Services, Policy, and Practice, Alpert Medical School of Brown University, Rhode Island Hospital, and Miriam Hospital, Providence, R.I. (Beaudoin); Institute for Trauma Recovery (An, Linnstaedt, McLean), Department of Anesthesiology (An, Linnstaedt), Department of Psychiatry (McLean), and Department of Emergency Medicine (McLean), University of North Carolina at Chapel Hill; Departments of Psychiatry and Neurology, University of California San Francisco, San Francisco (Neylan); Department of Biomedical Engineering, Georgia Institute of Technology, and Emory University, Atlanta (Clifford); Many Brains Project, Belmont, Mass. (Germine); Department of Emergency Medicine, University of Massachusetts Chan Medical School, Worcester (Haran); Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, Tenn. (Storrow); Department of Emergency Medicine, Henry Ford Health System, Detroit (Lewandowski); Department of Emergency Medicine, Indiana University School of Medicine, Indianapolis (Musey); Department of Emergency Medicine, University of Florida College of Medicine-Jacksonville (Hendry, Sheikh); Department of Emergency Medicine, Cooper Medical School of Rowan University, Camden, N.J. (Jones); Department of Emergency Medicine, University of Cincinnati College of Medicine, and College of Nursing, University of Cincinnati, Cincinnati (Punches); Department of Emergency Medicine, Oakland University William Beaumont School of Medicine, Rochester, Mich. (Swor); Department of Emergency Medicine, Boston Medical Center, Boston (McGrath); Department of Surgery and Department of Neurosurgery (Pascual), Department of Surgery, Division of Traumatology, Surgical Critical Care and Emergency Surgery (Seamon), and Perelman School of Medicine (Pascual, Seamon), University of Pennsylvania, Philadelphia; Department of Emergency Medicine, Einstein Healthcare Network, Philadelphia (Datner); Department of Emergency Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia (Datner); Department of Emergency Medicine, Jefferson University Hospitals, Philadelphia (Chang); Department of Emergency Medicine, Saint Joseph Mercy Hospital, Ypsilanti, Mich. (Domeier); Department of Emergency Medicine, University of Massachusetts Medical School-Baystate, Springfield (Rathlev); Department of Emergency Medicine, McGovern Medical School, University of Texas Health, Houston (Sergot); Department of Emergency Medicine, Brigham and Women's Hospital, Boston (Sanchez); National Center for PTSD, Behavioral Science Division, VA Boston Healthcare System, Boston (Miller); Department of Psychiatry, Boston University School of Medicine, Boston (Miller); National Center for PTSD, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven (Pietrzak); Department of Psychiatry, Yale School of Medicine, New Haven, Conn. (Pietrzak); Department of Psychology, Yale University, New Haven, Conn. (Joormann); Department of Psychological and Brain Sciences, Washington University in St. Louis (Barch); Department of Biosciences and Institute for Behavioral Medicine Research, OSU Wexner Medical Center, Columbus, Ohio (Sheridan); Department of Psychiatry, Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston (Smoller); Stanley Center for Psychiatric Research, Broad Institute, Cambridge, Mass. (Smoller); Department of Psychiatry, University of Pittsburgh, Pittsburgh (Luna); Department of Anesthesiology and Department of Internal Medicine-Rheumatology, University of Michigan Medical School, Ann Arbor (Harte); Kolling Institute of Medical Research, University of Sydney, St Leonards, New South Wales, Australia (Elliott); Faculty of Medicine and Health, University of Sydney, Northern Sydney Local Health District, New South Wales, Australia (Elliott); Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago (Elliott); Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston (Koenen); Lurie Center for Autism, Lexington, Mass. (Ravichandran).