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Updated: Sep 7, 2025

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
Functional Movement Disorder and Parkinson's Disease Comorbidity: A Case Report
Abstract:
Functional movement disorders (FMD) are abnormal involuntary movements that are not attributable to known neurological and neuroanatomical causes. In the past decade, FMD diagnoses have been based on positive factors that are inconsistent with neurological disorders and not on the exclusion of neurological disorders. In this report, we presented the case of a female patient who had been followed up for 4 years in multiple health centers with the diagnosis of a neurological disorder which was suspected in the previous 1 year to be of psychogenic origin. A neurological disorder comorbid with depression and FMD was diagnosed after admission as an inpatient to our clinic. By presenting this case, it was intended to emphasise the importance of follow up after diagnosing FMD, given its common basis with Parkinson's disease and the high incidence of comorbidites seen with it. Imaging and elecrophysiological techniques should be relied upon.for differentiating FMD and neurological diseases. Although psychological causes are significant disease risk and/or maintenance factors, they are not sufficient for explaining the aetiology of FMD, which requires a multidisciplinary approach. Keywords: Functional movement disorders, Parkinson's disease, DaTscan.
Insights
Functional movement disorders (FMD) require careful follow-up due to links with Parkinson's disease. Diagnosis necessitates a multidisciplinary approach, integrating imaging and psychological factors for accurate assessment.
Area of Science:
- Neurology
- Neuroscience
Background:
- Functional movement disorders (FMD) are characterized by abnormal involuntary movements without clear neurological causes.
- Recent diagnostic approaches for FMD focus on positive indicators rather than exclusion of neurological disorders.
Observation:
- A case study of a female patient with a 4-year history of misdiagnosed neurological disorder, suspected psychogenic origin.
- The patient was diagnosed with comorbid depression and FMD upon inpatient admission.
Findings:
- FMD shares commonalities with Parkinson's disease, highlighting the need for diligent follow-up.
- Imaging and electrophysiological techniques are crucial for differentiating FMD from neurological diseases.
- Psychological factors contribute to FMD risk and maintenance but do not fully explain its etiology.
Implications:
- Emphasizes the importance of comprehensive follow-up strategies for FMD patients.
- Underscores the necessity of a multidisciplinary approach involving neurological, psychological, and diagnostic imaging assessments.
- Suggests reliance on advanced techniques like DaTscan for accurate differential diagnosis.
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