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    Area of Science:

    • Machine Learning
    • Statistical Modeling
    • Data Science

    Background:

    • Area Under the ROC Curve (AUC) is a standard machine learning performance metric.
    • Two-way Partial AUC (TPAUC) offers a more refined evaluation by focusing on specific True Positive Rate (TPR) and False Positive Rate (FPR) regions.
    • Existing TPAUC metrics face challenges with optimization and consistency.

    Purpose of the Study:

    • To address the optimization challenges of TPAUC in machine learning.
    • To develop a novel framework for efficient end-to-end stochastic training of TPAUC.
    • To provide theoretical guarantees for the proposed optimization approach.

    Main Methods:

    • Development of a generic framework for constructing surrogate optimization problems for TPAUC.
    • Utilizing deep learning for efficient end-to-end training.
    • Theoretical analysis to bound the original TPAUC objective and ensure generalization.

    Main Results:

    • The proposed framework enables gradient-based optimization for TPAUC.
    • Theoretical analysis confirms the surrogate objective provides an upper bound for TPAUC.
    • Empirical studies demonstrate the framework's effectiveness on benchmark datasets.

    Conclusions:

    • The novel framework successfully optimizes TPAUC, overcoming previous limitations.
    • The approach facilitates high TPAUC performance with good generalization.
    • This work presents a significant advancement in optimizing advanced AUC metrics for machine learning.