Related Experiment Video
Updated: Sep 7, 2025

A Personalized 3D-Printed Model for Preoperative Evaluation in Thyroid Surgery
Published on: February 17, 2023
The Impact of Thyroid Diseases on Patients' Work Functioning: A Pilot Study.
Ilaria Vetrani1, Veruscka Leso, Luca Fontana
1From the Section of Occupational Medicine, Department of Public Health, University of Naples Federico II, Naples, Italy (Dr I. Vetrani, Dr Leso, Dr Fontana, Dr Spadarella, Dr Iavicoli); Section of Endocrinology, Department of Clinical and Surgery, University of Naples Federico II, Naples, Italy (Dr C. Vetrani); Section of Endocrinology, Department of Public Health, University of Naples Federico II, Naples, Italy (Dr Sessa, Dr Porcelli).
Thyroid diseases (TDs) negatively impact work ability (WA), with TD workers reporting lower scores than healthy individuals. Factors like specific TD types and job duration further influence perceived WA.
Area of Science:
- Endocrinology
- Occupational Health
- Public Health
Background:
- Thyroid diseases (TDs) are common endocrine disorders.
- Assessing the impact of TDs on work ability (WA) is crucial for employee well-being and productivity.
- Limited research exists on the specific factors influencing WA in TD patients.
Purpose of the Study:
- To investigate the impact of thyroid diseases on patients' work ability.
- To identify factors influencing work ability in individuals with thyroid diseases.
Main Methods:
- A case-control study involving 150 workers with thyroid diseases and matched healthy controls.
- Work Ability Index (WAI) was utilized to assess perceived work ability.
- Data collected between May 2020 and November 2021.
Main Results:
- Thyroid disease workers reported significantly lower mean WA scores (39 ± 6) compared to controls (43 ± 4).
- Graves disease and follicular carcinoma were associated with the poorest WA perception.
- Presence of a thyroid disease (β = -0.396) and longer job duration (β = -0.173) were linked to reduced work ability.
Conclusions:
- Thyroid diseases demonstrably affect work ability, necessitating targeted support.
- Interdisciplinary management strategies are recommended to support the personal, social, and professional lives of affected workers.
Related Concept Videos
Functions of Thyroid Hormones
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
Synthesis and Regulation of Thyroid Hormones
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Major Hormones and Their Functions
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
Hormones and Bone Tissue
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Synthesis and Functions of Calcitonin
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...

