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Blind Procedures

Blind Procedures

Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...

Blinding

Blinding

Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.

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Related Experiment Video

Updated: Sep 7, 2025

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

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CANreduce-SP-adding psychological support to web-based adherence-focused guided self-help for cannabis users: study

J I Mestre-Pintó^1,2, F Fonseca^3,4,5, M P Schaub⁶

¹Addiction Research Group (GRAd), Neuroscience Research Program, Hospital del Mar Medical Research Institute (IMIM), 08003, Barcelona, Spain. jmestre@imim.es.

|June 22, 2022

Summary

This study evaluates CANreduce 2.0, a web-based tool for problematic cannabis users. It assesses if the tool, with or without psychological support, effectively reduces cannabis consumption compared to standard care.

Keywords:

Adherence CANreduce Cannabis use disorder Cognitive behavioural therapy Guidance Psychological support Randomized controlled trial Reducing cannabis Self-help tool

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Published on: January 17, 2025

Area of Science:

Clinical Psychology
Digital Health Interventions
Substance Use Disorders

Background:

Cannabis is Europe's most used illicit drug, with rising treatment demand in Spain.
Problematic cannabis users often do not seek traditional treatment.
Web-based tools like CANreduce 2.0 offer a potential solution for managing cannabis use.

Purpose of the Study:

To evaluate the effectiveness of the Spanish version of CANreduce 2.0 (CANreduce-SP) in reducing cannabis use.
To determine if adding psychological support to CANreduce-SP enhances its efficacy.
To compare CANreduce-SP interventions against treatment as usual (TAU).

Main Methods:

A three-arm randomized controlled trial (RCT) protocol is described.
Intervention groups: (1) CANreduce-SP with psychological support, (2) CANreduce-SP alone, (3) TAU.
Primary outcome: change in weekly cannabis use days; secondary outcomes: other cannabis use measures. Mental disorders explored as predictors.

Main Results:

This section is for results that will be available after the study is completed.

Conclusions:

The study will determine CANreduce-SP's effectiveness in reducing cannabis use frequency and quantity.
It will investigate whether psychological support improves outcomes for problematic cannabis users.