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Editorial: Focus feature on biomarkers in network neuroscience
Linda Douw1, Mario Senden2,3, Martijn van den Heuvel4,5
1Department of Anatomy and Neurosciences, Amsterdam Neuroscience, UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Network Neuroscience (Cambridge, Mass.)
|June 23, 2022
Summary
Novel network biomarkers are needed in clinical neuroscience. This study explores their potential to differentiate neurological and psychiatric disorders, despite shared network characteristics.
Area of Science:
- Neuroscience
- Biomarker Discovery
- Systems Neuroscience
Background:
- Accurate diagnosis of neurological and psychiatric disorders is challenging due to overlapping symptoms.
- Current diagnostic methods struggle with the heterogeneity of these conditions.
- There is a critical need for objective biomarkers in clinical neuroscience.
Discussion:
- Network-based biomarkers are proposed as a potential solution for differential diagnosis.
- Investigating shared network characteristics across disorders is crucial.
- Assessing the differentiating power of network biomarkers is the central question.
Key Insights:
- Network biomarkers may offer improved diagnostic capabilities in clinical neuroscience.
- Understanding shared versus distinct network features is key to biomarker development.
- The focus feature critically examines the utility of network approaches.
Outlook:
- Future research should focus on validating network biomarkers in diverse patient populations.
- Developing robust methodologies for network analysis in clinical settings is essential.
- Network neuroscience holds promise for advancing personalized medicine in psychiatry and neurology.

