Kimura's disease and its masquerade with a malignancy: A case report
Fareeha Farooqui1, Ibad Ur Rehman1, Sania Waseem1
1Shifa International Hospital, Islamabad, Pakistan.
Annals of Medicine and Surgery (2012)
|June 23, 2022
Summary
Kimura's disease, a rare chronic condition, presents with characteristic eosinophilia and swelling. Surgical removal followed by radiation offers a favorable prognosis for this benign condition.
Area of Science:
- Head and Neck Surgery
- Dermatology
- Oncology
Background:
- Kimura's disease is a rare, benign inflammatory condition often misdiagnosed as malignancy.
- Predominantly affects young males in Southeast Asia, presenting with head and neck swellings.
Observation:
- A 29-year-old male presented with an 8-year history of painless, gradually enlarging left parotid and post-auricular masses.
- The patient was asymptomatic throughout the disease progression.
Findings:
- Diagnosis was confirmed via histology and immunohistochemistry, revealing characteristic features of Kimura's disease.
- Key indicators include eosinophilia, follicular hyperplasia, and elevated immunoglobulin E (IgE) levels.
Implications:
- Early diagnosis and appropriate treatment, including surgery and radiation, are crucial for managing Kimura's disease.
- The condition has a favorable prognosis with no reported malignant transformations.
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