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Updated: Sep 7, 2025
Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs
Published on: March 2, 2018
[Genetics and neurodevelopmental disorders]
Background:
Current developments in genetic strategies result in tracing an underlying genetic defect in the majority of neurodevelopmental disorders (NDD) patients, including those with normal functioning as well as intellectual disabilities. These genetic NDD are increasingly detected and still often underexposed in psychiatric practice.
Aim:
To improve (early) detection of these genetic NDD to contribute to psychiatric diagnostics and treatment, with the emphasis on reducing the mental vulnerabilities per developmental stage.
Method:
Overview of developments based on literature and guidelines.
Results:
Early detection includes both biological and environmental factors and provides tools for specific diagnostic procedures and treatment strategies. Within scientific research there is a tendency to translational research, which includes all levels from cell to the entire organism. This offers new insights and possibilities for personalized treatment.
Conclusion:
The current fragmented knowledge on these rare disorders needs to be bundled in the upcoming years. There is a lot of ground to be gained for psychiatric practice in this area.
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