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Published on: October 2, 2016
Two new aspidosperma-type monoterpenoid indole alkaloids from Ervatamia officinalis
Bao-Jing Li1, Yan Ma2, Hai-Shan Qian1
1College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China.
Abstract:
Two new aspidosperma-type monoterpenoid indole alkaloids, 16-O-methylvoafinine (1) and 14,15-diepi-voafinidine (2) were isolated from the aerial parts of Ervatamia officinalis. Their structures were established by comprehensive spectroscopic analysis including 1D and 2D NMR, HR-ESI-MS, and electronic circular dichroism calculation. The isolated compounds were evaluated for cytotoxic activities against HepG2, MCF-7, and A549 cell lines by CCK-8 assay.

