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Published on: August 8, 2025
Structured Allocation of Transcatheter Aortic Valve Replacement Patients during Coronavirus Disease 2019 Pandemic:
Nora Berisha1, Kathrin Klein1, Verena Veulemans1
1Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich Heine University, Moorenstr. 5, 40225 Düsseldorf, Germany.
Insights
During COVID-19, an allocation algorithm prioritized sicker patients for Transcatheter Aortic Valve Replacement (TAVR). This ensured safe and efficient procedures, even with resource limitations, and shortened hospital stays.
Area of Science:
- Cardiology
- Healthcare Management
- Public Health
Background:
- The Coronavirus Disease 2019 (COVID-19) pandemic led to medical resource shortages.
- Transcatheter Aortic Valve Replacement (TAVR) procedures require careful resource allocation.
- An allocation algorithm was implemented to manage TAVR during the pandemic.
Purpose of the Study:
- To investigate the impact of a TAVR allocation algorithm on patient selection.
- To evaluate procedural outcomes and hospital resource utilization post-algorithm implementation.
- To assess the safety and efficiency of TAVR during pandemic-related resource constraints.
Main Methods:
- Comparative analysis of 456 TAVR patients before (pre-COVID-19) and 456 patients after (COVID-19) algorithm implementation.
- Assessment of patient characteristics, including cardiac decompensations, angina severity, troponin levels, and left ventricular ejection fraction (LVEF).
- Evaluation of procedural characteristics (predilatations, procedural time) and hospital resource utilization (in-hospital stay, monthly patient volume).
Main Results:
- The COVID-19 group presented with sicker patients: higher rates of cardiac decompensations, severe angina, elevated troponin, and reduced LVEF.
- Procedural characteristics showed increased predilatations and longer procedural times in the COVID-19 group.
- Despite increased patient acuity, TAVR success rates remained high, with no difference in safety parameters. The COVID-19 group experienced shorter in-hospital stays and fewer patients treated monthly.
Conclusions:
- The TAVR allocation algorithm effectively prioritized sicker patients during the COVID-19 pandemic.
- The algorithm facilitated efficient and safe TAVR procedures, comparable to pre-pandemic outcomes.
- Implementation of the algorithm contributed to a reduction in in-hospital stay duration.
Abstract:
Due to shortages of medical resources during the Coronavirus Disease 2019 (COVID-19) pandemic, an allocation algorithm for Transcatheter Aortic Valve Replacement (TAVR) was established. We investigated the impact on patient selection and procedural results. In total, 456 TAVR patients before (pre-COVID-19 group) and 456 TAVR patients after (COVID-19 group) the implementation of our allocation algorithm were compared. Concerning patient characteristics, the COVID-19 group revealed a higher rate of cardiac decompensations/cardiogenic shocks (10.5% vs. 1.3%; p < 0.001), severe angina pectoris (Canadian Cardiovascular Society (CCS) II, III and IV: 18.7% vs. 11.8%; p = 0.004), troponin elevation (>14 ng/L: 84.9% vs. 77%; p = 0.003) and reduced left ventricular ejection fraction (LVEF) (<45%: 18.9% vs. 12%; p = 0.006). Referring to procedural characteristics, more predilatations (46.3% vs. 35.1%; p = 0.001) and a longer procedural time (80.2 min (+/−29.4) vs. 66.9 min (+/−17.5); p < 0.001) were observed. The success rate was evenly high; no differences in safety parameters were reported. Examining the utilization of hospital resources, the COVID-19 group showed a shorter in-hospital stay (8.4 days (+/−5.9) vs. 9.5 days (+/−9.33); p = 0.041) and fewer TAVR patients were treated per month (39 (+/−4.55) vs. 46.11 (+/−7.57); p = 0.03). Our allocation algorithm supported prioritization of sicker patients with similar efficient and safe TAVR procedures. In-hospital stay could be shortened.
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