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Duodenal G- and D-cell changes following corticosteroid administration. Immunocytochemical long-term study in guinea
Klinische Wochenschrift
|February 2, 1987
Abstract:
Prednisolone administration in guinea pigs for 20 days induces significant hypergastrinemia and duodenal G-cell hyperplasia. Hypergastrinemia and duodenal G-cell hyperplasia are less prominent following 40 days of prednisolone administration and this could be partly attributed to the duodenal D-cell increased activity, which represents an adaptive response to the alterations of gastric secretory functions induced by corticosteroids.