Related Experiment Video
Updated: Sep 6, 2025

Quantification of the Potential Impact of Glyphosate-Based Products on Microbiomes
Published on: January 10, 2022
Glyphosate, Roundup and the Failures of Regulatory Assessment
1Clare Hall, University of Cambridge, Herschel Road, Cambridge CB3 9AL, Cambridgeshire, UK.
Abstract:
Roundup is the most widely used herbicide in agriculture. It contains glyphosate as the 'active ingredient', together with formulants. There are various versions of Roundup, with somewhat different effects depending on the formulants. Most genetically-modified crops are designed to tolerate Roundup, thus allowing spraying against weeds during the growing season of the crop without destroying it. Having been so heavily used, this herbicide is now found in the soil, water, air, and even in humans worldwide. Roundup may also remain as a residue on edible crops. Many studies have found harm to the environment and to health, making it imperative to regulate the use of Roundup and to ensure that its various formulations pose no danger when used in the long-term. Unfortunately, regulators may only assess the 'active ingredient', glyphosate, and ignore the toxicity of the formulants, which can be far more toxic than the active ingredient. This omission is in violation of a ruling by the Court of Justice of the European Union. There are close ties between the regulators and the industry they are supposed to regulate. Objectionable practices include 'revolving doors' between the regulators and the industry, heavy reliance on unpublished papers produced by the industry while dismissing papers published by independent scientists, and strong covert influence on the regulatory process by industry. Although this paper focuses on the European Union (EU), the situation is much the same in the United States.
Related Concept Videos
Drug Regulation
Hypothesis: Accept or Fail to Reject?
There are two ways to indicate that the null hypothesis is not rejected. 'Accept' the null...
Drug Control Governance: Regulatory Bodies and Their Impact
Global Regulatory Systems
Mutagenicity and Carcinogenicity

