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Updated: Aug 19, 2026

Reproducable Paraplegia by Thoracic Aortic Occlusion in a Murine Model of Spinal Cord Ischemia-reperfusion
Published on: March 4, 2014
Paraplegia after ductus ligation accompanied by injury to intercostal artery
Insights
Surgical repair of patent ductus arteriosus can lead to paraplegia, a previously unreported complication. This rare outcome occurred in a child following ductus ligation and intercostal artery injury.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Neurology
Background:
- Patent ductus arteriosus (PDA) is a common congenital heart defect in infants.
- Surgical ligation is a standard treatment for PDA when medical management fails.
- Complications of PDA surgery are generally well-documented, but new adverse events can emerge.
Observation:
- A 5-year-old girl underwent surgical ligation for PDA.
- The procedure involved ligation of the ductus arteriosus and injury to an intercostal artery.
- Post-operatively, the patient developed paraplegia.
Findings:
- Paraplegia is identified as a novel complication following surgical PDA treatment.
- The complication appears linked to surgical trauma, specifically injury to an intercostal artery during ductus ligation.
- This case highlights a potential neurological risk associated with PDA surgery.
Implications:
- This finding necessitates a review of surgical techniques for PDA to minimize neurological risks.
- Clinicians should be aware of the potential for paraplegia as a rare complication.
- Further research is warranted to understand the mechanism and incidence of this complication.
Abstract:
Paraplegia is a hitherto unreported complication of the surgical treatment of patent ductus arteriosus. This communication presents the case history of a 5-year-old girl in whom this serious complications developed after ductus ligation accompanied by injury to an intercostal artery.
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