Related Experiment Video
Updated: Sep 6, 2025

07:06
Bone Marrow-derived Macrophage Production
Published on: November 22, 2013
73.9K
Macrophages in Health and Non-Infectious Disease 2.0
Evgeny E Bezsonov1,2,3, Alexei Gratchev4, Alexander N Orekhov1,2
1Laboratory of Angiopathology, Institute of General Pathology and Pathophysiology, 8 Baltiiskaya Street, 125315 Moscow, Russia.
Biomedicines
|June 24, 2022
Summary
Macrophages are key immune cells involved in maintaining body balance (homeostasis) and causing non-infectious diseases. This collection explores their latest regulatory mechanisms and disease roles.
Area of Science:
- Immunology
- Cell Biology
- Pathogenesis
Background:
- Macrophages are critical immune cells involved in maintaining tissue homeostasis.
- Dysregulation of macrophage function contributes to various non-infectious diseases.
Discussion:
- This Special Issue compiles recent research on macrophage regulatory mechanisms.
- Focuses on the intricate roles macrophages play in non-infectious disease development.
Key Insights:
- Elucidates the complex mechanisms macrophages employ to maintain physiological balance.
- Highlights the significant involvement of macrophages in the progression of various non-infectious conditions.
Outlook:
- Advances in understanding macrophage biology offer potential for novel therapeutic interventions.
- Future research directions aim to harness macrophage functions for disease treatment.
More Related Videos
Related Concept Videos
Immune Surveillance by NK Cells and Phagocytes
2.6K
Immune surveillance is an integral part of the innate immune system, involving the continuous monitoring of peripheral tissues to detect and respond to pathogens, infected cells, or cancerous cells. This surveillance is conducted primarily by natural killer (NK) cells and phagocytes, which employ distinct but complementary mechanisms to identify and eliminate threats.
Natural Killer Cells: The Fast Responders
NK cells are large granular lymphocytes found in the blood and lymphatic system. These...
Natural Killer Cells: The Fast Responders
NK cells are large granular lymphocytes found in the blood and lymphatic system. These...
2.6K
Inflammation
55.0K
Overview
55.0K
Cells of the Innate Immune Response
3.0K
The innate immune response is an immediate and non-specific response against pathogens, acting swiftly to prevent the spread of infections. The primary cells involved in this response are phagocytes and natural killer (NK) cells.
Phagocytes
Phagocytes police the peripheral tissues by removing cellular debris and responding to the invasion of foreign substances or pathogens. Many phagocytes attack and remove microorganisms even before lymphocytes detect them. The human body has two general...
Phagocytes
Phagocytes police the peripheral tissues by removing cellular debris and responding to the invasion of foreign substances or pathogens. Many phagocytes attack and remove microorganisms even before lymphocytes detect them. The human body has two general...
3.0K
Cell-mediated Immune Responses
71.6K
Overview
71.6K
Inflammatory Response
6.8K
An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
6.8K
Phagocytosis of Apoptotic Cells
4.0K
Cells undergoing apoptosis form apoptotic bodies that must be removed immediately to prevent inflammation, autoimmune diseases, and necrosis. Phagocytosis is carried out by professional phagocytes such as macrophages or immature dendritic cells. Non-professional phagocytes such as epithelial cells and fibroblasts also take part in this process; however, they are not as effective as professional phagocytes.
Normal cells contain receptors that prevent them from being recognized...
Normal cells contain receptors that prevent them from being recognized...
4.0K

