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Pediatric Procedural Sedation and Analgesia (PROSA) in the Leuven University Hospitals: An Audit on Efficacy and

Lotte Kerkhofs1, Karel Allegaert2,3,4,5, Jaan Toelen2,3,6

  • 1Faculty of Medicine, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.

Children (Basel, Switzerland)
|June 24, 2022
PubMed

Insights

The Pediatric Sedation (PROSA) team initiative achieved a 98% success rate in pediatric procedural sedation, demonstrating its effectiveness and safety. Adverse events were low at 2%, with no reported deaths, highlighting the program

Area of Science:

  • Pediatric Anesthesiology
  • Patient Safety in Healthcare
  • Sedation Management

Background:

  • Hospitals can be stressful environments for children.
  • Increased demand for pediatric procedural sedation necessitates dedicated teams.
  • The PROSA team initiative was established in 2014 at Leuven University Hospitals.

Purpose of the Study:

  • To assess the efficacy and safety of the PROSA team initiative since its inception.
  • Evaluate the success and complication rates of pediatric procedural sedation.
  • Analyze data from a large cohort of pediatric procedures requiring sedation.

Main Methods:

  • Prospective registration of demographic and clinical data by the PROSA team.
  • Anonymized data extraction from November 2014 to June 2021.
  • Analysis of 5090 procedures involving pediatric procedural sedation.

Main Results:

  • Successful sedation in 98% of patients; 3.3% classified as technically difficult.
  • Procedure failure in 2% of cases, primarily due to inadequate sedation or logistic issues.
  • Overall adverse event incidence of 2%, predominantly during gastro-coloscopy or bronchoscopy; no deaths reported.

Conclusions:

  • The PROSA team initiative is effective, achieving a 98% success rate in pediatric procedural sedation.
  • The program demonstrates a favorable safety profile with a 2% adverse event rate.
  • Current training and implementation of the PROSA team ensure efficient and safe sedation practices for children.

Keywords:
anesthesianon-pharmacological sedationpediatricsprocedural sedation and analgesia

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