Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Intracranial blastomycoma.

K L Roos, J P Bryan, W W Maggio

    Medicine
    |May 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Central nervous system (CNS) blastomycosis can present as solitary brain masses, not just meningitis. These blastomycomas, often diagnosed via tissue and culture, are treatable with antifungals or surgery.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Epidural Hematoma in Lacrosse.

    The Physician and sportsmedicine·2016
    Same author

    Preoperative embolization of intracranial meningiomas: efficacy, technical considerations, and complications.

    AJNR. American journal of neuroradiology·2014
    Same author

    An enhancing brainstem lesion in a patient with a history of worldwide travel.

    Neurology·2011
    Same author

    Address.

    Public health papers and reports·2009
    Same author

    ASSESSMENT OF THE NATURAL HISTORY OF ANTERIOR COMMUNICATING ANEURYSMS.

    Journal of neurosurgery·2009
    Same author

    Bilateral intracavernous carotid artery pseudoaneurysms as a result of sellar reconstruction during the transsphenoidal resection of a pituitary macroadenoma: case report.

    Minimally invasive neurosurgery : MIN·2009
    Same journal

    A meta-analysis of the effects of Baduanjin training on the human body temperature based on infrared thermography technology.

    Medicine·2026
    Same journal

    The predictive ability of "TyG_CVAI" for incident stroke in individuals with different glycemic metabolic status: A national cohort study.

    Medicine·2026
    Same journal

    Symptoms and quality of life in gynecological cancer patients after surgery: Application of latent profile and network analysis.

    Medicine·2026
    Same journal

    Massive hemoptysis as the initial presentation of Behçet disease complicated by multisite thromboembolism: A case report.

    Medicine·2026
    Same journal

    Dextromethorphan-bupropion-associated pharmacovigilance signals based on the FAERS database: An observational study.

    Medicine·2026
    Same journal

    Effects of Mulligan sustained natural apophyseal glide mobilizations on pain, mobility, and lumbar-related disability in chronic non-specific low back pain: A systematic review and meta-analysis.

    Medicine·2026
    See all related articles

    Area of Science:

    • Mycology
    • Neurology
    • Infectious Diseases

    Background:

    • Blastomycosis is a fungal infection primarily affecting the lungs, but it can spread to the central nervous system (CNS).
    • While CNS blastomycosis commonly manifests as meningitis, solitary intracranial mass lesions (blastomycomas) are also recognized presentations.

    Observation:

    • Four patients with solitary intracranial blastomycomas presented with focal neurological deficits.
    • Most patients lacked clear extraneural blastomycosis, and diagnostic tests like complement fixation and immunodiffusion were negative.
    • Computerized tomography (CT) scans showed single mass lesions with enhancement and edema, often misdiagnosed as tumors.

    Findings:

    • Diagnosis was confirmed through intraoperative tissue wet mount, lung lesion culture, or ventricular fluid analysis.

    Related Experiment Videos

  • Cerebrospinal fluid cultures from lumbar punctures were consistently negative.
  • All four patients survived, with two treated successfully with Amphotericin B and one with surgical removal.

    • Implications:

    • Solitary intracranial blastomycomas may be more common than previously assumed, especially in endemic areas.
    • CT findings suggestive of a mass lesion in endemic regions should prompt consideration of CNS blastomycoma, even without systemic signs.
    • Definitive diagnosis relies on histopathology and culture, highlighting the importance of these methods in clinical practice.