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Related Experiment Video

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A Rehabilitation Program of Exoskeleton-assisted Body Weight-Supported Treadmill Training with Non-immersive Virtual Reality for Stroke Patients
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Stance Phase Gait Training Post Stroke Using Simultaneous Transcranial Direct Current Stimulation and Motor

Ahlam Salameh1,2,3, Jessica McCabe1, Margaret Skelly1

  • 1VA Northeast Ohio Healthcare System, Cleveland, OH 44106, USA.

Brain Sciences
|June 24, 2022
PubMed
Summary

This study shows that combining brain stimulation with virtual reality gait training improved walking speed and function in chronic stroke survivors. This novel protocol offers a feasible approach for targeted stroke rehabilitation.

Keywords:
Transcranial Direct Current StimulationVRbrain stimulationgaitneurological rehabilitationphysical therapystroketDCSvirtual reality

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Area of Science:

  • Neuroscience
  • Rehabilitation Medicine
  • Biomechanics

Background:

  • Gait deficits persist in many stroke survivors, limiting mobility.
  • Current rehabilitation strategies do not fully restore normal gait for all individuals.
  • There is a need for targeted therapies addressing individual post-stroke gait impairments.

Purpose of the Study:

  • To develop and evaluate a combined protocol of Transcranial Direct Current Stimulation (tDCS) and focused stance phase gait training.
  • To assess the feasibility and efficacy of this protocol in individuals with chronic stroke (>6 months post-stroke).
  • To investigate improvements in gait speed, functional mobility, and lower extremity coordination.

Main Methods:

  • A 10-session intervention combining bihemispheric tDCS with Virtual Reality (VR)-assisted treadmill training and overground practice.
  • Training incorporated motor learning (ML) principles focused on stance phase deficits.
  • Outcome measures included gait speed, Timed Up and Go (TUG), Functional Gait Assessment (FGA), and Fugl−Meyer for lower extremity (FMLE).

Main Results:

  • The protocol was feasible to administer in individuals with chronic stroke.
  • Significant improvements were observed in gait speed (0.25 ± 0.11 m/s) and FGA (4.55 ± 3.08 points).
  • Statistically significant improvements were also noted in TUG (2.36 ± 3.81 s) and FMLE (4.08 ± 1.82 points).

Conclusions:

  • A 10-session intervention combining tDCS and ML-based gait rehabilitation is feasible.
  • This combined approach yielded clinically meaningful improvements in gait function and lower extremity coordination.
  • The protocol shows promise for individuals with chronic stance phase deficits post-stroke.