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Updated: Sep 6, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Dispirooxindole-β-Lactams: Synthesis via Staudinger Ketene-Imine Cycloaddition and Biological Evaluation

Vadim E Filatov1, Dmitrii A Iuzabchuk1, Viktor A Tafeenko1

  • 1Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, 119234 Moscow, Russia.

International Journal of Molecular Sciences
|June 24, 2022
PubMed

Keywords:
Staudinger reactionketene-imine cycloadditionoxo-pyrrolidine-3-carboxylic acidsspirooxindolesβ-lactams

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