The Therapeutic Potential of Milk Extracellular Vesicles on Colorectal Cancer

Area of Science:

• Oncology
• Biotechnology
• Nanomedicine

Background:

• Colorectal cancer is a leading cause of cancer death globally.
• Current chemotherapies lack selectivity, harming healthy cells and causing severe side effects.
• Targeted therapies are crucial for improving cancer treatment efficacy and safety.

Purpose of the Study:

• To review the biogenesis, isolation, and characterization of milk-derived extracellular vesicles (EVs).
• To explore the therapeutic potential of milk EVs, particularly in the context of colorectal cancer.
• To highlight milk EVs as a natural and selective anti-cancer agent.

Main Methods:

• Literature review on milk EV research.
• Analysis of studies detailing EV biogenesis and isolation techniques.
• Examination of research on the anti-tumor effects of milk EVs.

Main Results:

• Milk EVs from various sources, including camels and cows, demonstrate significant tumor-suppressive properties.
• These EVs can be isolated and characterized using established methods.
• The molecular composition of milk EVs contributes to their targeted therapeutic effects.

Conclusions:

• Milk-derived EVs represent a promising natural product for developing targeted colorectal cancer therapies.
• Their selective action against tumor cells offers a potential advantage over conventional chemotherapy.
• Further research into milk EVs could lead to more effective and safer cancer treatments.