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The Greek Collaborative Long COVID Study: Non-Hospitalized and Hospitalized Patients Share Similar Symptom Patterns

Martha-Spyridoula Katsarou1,2,3, Eleni Iasonidou2, Alexander Osarogue4

  • 1Research Group of Clinical Pharmacology and Pharmacogenomics, Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, 15771 Zografou, Greece.

Journal of Personalized Medicine
|June 24, 2022
PubMed

Insights

Long COVID-19 syndrome, affecting 3-12% globally, causes persistent symptoms over 12 weeks. This study highlights the diverse symptoms and challenges faced by patients, regardless of initial hospitalization severity.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Epidemiology

Background:

  • Long COVID-19 syndrome is defined as persistent symptoms exceeding 12 weeks post-coronavirus infection.
  • Estimates suggest 3% to 12% of global COVID-19 patients experience Long COVID.
  • The syndrome's characteristics, symptoms, and patient challenges require further investigation.

Purpose of the Study:

  • To estimate the characteristics, symptoms, and challenges faced by Long COVID patients in Greece.
  • To collaborate with a Long COVID patient organization for data collection.

Main Methods:

  • A qualitative study utilizing anonymized online questionnaires with free-text entries.
  • Data collected from 208 Long COVID patients.

Main Results:

  • 68.8% of respondents were not hospitalized.
  • 66.8% reported lingering symptoms for over six months.
  • Eighteen distinct symptoms were reported, including fatigue, palpitations, shortness of breath, and parosmia, in both hospitalized and non-hospitalized patients.
  • Low awareness of Long COVID sequelae among medical professionals was noted.
  • Targeted rehabilitation programs are largely unavailable or not integrated into patient management plans.

Conclusions:

  • Long COVID patients with initially mild symptoms experience similar persistent symptoms to those who were hospitalized.
  • Long COVID syndrome is a multi-systemic condition.
  • A multidisciplinary medical approach is essential for accurate diagnosis and effective management of Long COVID patients.

Keywords:
Long COVIDpost-COVIDpost-acute COVID (PACS)post-acute sequelae of COVID-19 (PASC)

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