Related Experiment Video
Updated: Aug 9, 2026

Discovery of New Intracellular Pathogens by Amoebal Coculture and Amoebal Enrichment Approaches
Published on: October 27, 2013
Retrospective identification of Acanthamoeba culbertsoni in a case of amoebic meningoencephalitis
Abstract:
Acanthamoeba culbertsoni was identified retrospectively in a case of amoebic meningoencephalitis, previously reported by Jager and Stamm (Lancet, 2, 1343, 1972). This is the second report of this species causing secondary infection in man. Positive results were obtained only with anti-A. culbertsoni sera when the brain sections were stained by the indirect immunofluorescence antibody test with various antisera produced against different Acanthamoeba species. Antiserum raised against purified plasma membranes of A. culbertsoni showed once more its highly specific diagnostic value.
Related Concept Videos
Viral Meningitis
Cryptococcal Meningitis
Amebiasis
Bacterial Meningitis I: Introduction
Brain Abscess l: Introduction

