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Periodic alternating gaze: a case without any hemispheric lesion.
Neurosurgery
|March 1, 1987
Summary
Periodic alternating gaze (PAG), typically linked to widespread brain ischemia, was studied in a patient with a localized crus cerebri lesion. This case challenges the conventional understanding of PAG
Area of Science:
- Neuroscience
- Neurology
- Clinical Pathophysiology
Background:
- Periodic alternating gaze (PAG) is a rare nystagmus variant.
- PAG is conventionally associated with bilateral cerebral hemispheric ischemia.
Observation:
- A unique case of periodic alternating gaze (PAG) in a patient is presented.
- The patient exhibited a highly localized lesion.
- The lesion was specifically identified in the crus cerebri.
Findings:
- The anatomical lesion causing PAG was restricted to the crus cerebri.
- This finding contrasts with the typical association of PAG with bilateral cerebral hemispheric ischemia.
- The study discusses the specific anatomical pathways and mechanism underlying PAG in this case.
Implications:
- This case expands the understanding of the neuroanatomical basis of periodic alternating gaze (PAG).
- It suggests that PAG can arise from focal lesions in specific brainstem pathways.
- Further research into the pathophysiology of PAG is warranted.