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Updated: Sep 6, 2025

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
A Case Report of Severe Dehydration Associated With Acute Kidney Injury Causing Acute ST-Segment Elevation Myocardial
Hosam Zaky1, Sadeq Tabatabai1, Parveez A Zarger1
1Cardiology Department, Dubai Hospital, Dubai Health Authority, Dubai, ARE.
Insights
Severe dehydration can trigger acute myocardial infarction (heart attack) in young men. This case highlights the importance of hydration for preventing heart attacks in at-risk individuals.
Area of Science:
- Cardiology
- Internal Medicine
- Environmental Health
Background:
- Acute myocardial infarction (AMI) in young adults presents diagnostic challenges.
- Common causes include thrombosis, dissection, and anatomical variations.
- The role of environmental factors like dehydration is less understood.
Abstract:
The initial electrocardiogram finding in the setting of acute myocardial infarction typically shows either persistent ST-segment elevation or non-ST-segment elevation. In young adults, when coronary angiography is performed, can further classify the patient with an occluded vessel and those with non-occluded coronary arteries. In these subgroups, myocardial infarction can be explained on the basis of coronary artery thrombosis, embolization, spontaneous coronary artery dissection, myocardial bridging, coronary aneurysms, ectasia, anomalous origin of coronary arteries coronary microvascular dysfunction, and vasospasm, or a combination of these factors. We describe a 37-year-old male with a history of chest pain and electrocardiographic evidence of acute myocardial infarction who worked many hours under the sun before being presented to the emergency department. The initial laboratory tests showed evidence of acute kidney injury. He underwent a rescue coronary angiogram due to failed initial medical reperfusion therapy with Tenecteplase, which revealed occluded of the distal left anterior descending (LAD) artery with a minor lesion in proximal LAD and right coronary artery. Our patient experienced acute myocardial infarction owing to severe dehydration. This case is important as it highlights that severe dehydration can be considered one of the triggering factors for acute myocardial infarction in young men who are at risk. Proper hydration could be a preventive measure.
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