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Updated: Sep 6, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Published on: December 19, 2020

Post COVID-19 Chronic Parenchymal Lung Changes.

Abdelfattah Touman¹, Mohammed Kahyat¹, Adeeb Bulkhi²

¹Department of Pulmonology, King Abdullah Medical City, Makkah, SAU.

|June 24, 2022

Summary

Persistent lung changes after COVID-19 are linked to invasive mechanical ventilation and a high neutrophil-lymphocyte ratio (NLR) at admission. These factors, not initial illness severity, predict long-term parenchymal lung issues.

Keywords:

complication covid-19 interstitial lung disease long covid post-covid-19 fibrosis

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Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

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Published on: December 19, 2020

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Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

Published on: June 21, 2024

Area of Science:

Pulmonology
Infectious Diseases
Radiology

Background:

Persistent parenchymal lung changes are a significant long-term complication of COVID-19.
Limited data exists on the characteristics and progression of these post-COVID-19 lung sequelae.
Understanding risk factors is crucial for managing long-term respiratory health after infection.

Purpose of the Study:

To evaluate persistent COVID-19-related parenchymal lung changes at 10 weeks post-acute pneumonia.
To identify clinical and laboratory risk factors associated with these persistent lung changes.
To differentiate between patients with persistent changes and those with rapid recovery.

Main Methods:

Retrospective case-control observational study of 38 COVID-19 patients.
Patients evaluated at a post-COVID-19 interstitial lung disease (ILD) clinic.
Comparison of 19 patients with persistent changes (Group 1) versus 19 with accelerated improvement (Group 2).

Main Results:

Group 1 exhibited more severe clinical and radiological disease with higher inflammatory markers.
Neutrophil-lymphocyte ratio (NLR) > 3.13 at admission was a significant risk factor (OR 6.42-5.92).
Invasive mechanical ventilation was a strong predictor (OR 13.09-44.5) of persistent parenchymal changes.

Conclusions:

Invasive mechanical ventilation and admission NLR > 3.13 are key risk factors for persistent lung changes post-COVID-19.
Neither acute illness severity nor radiological findings predicted these long-term changes.
Medications used during acute illness did not appear to influence the risk of developing persistent lung sequelae.