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Updated: Sep 6, 2025

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
Life-threatening obsessive-compulsive disorder precipitated by the COVID-19 pandemic in an adolescent
Ahrane Jayakumar1, Javier Sanchez-Cerezo1,2, Afshan Khayam3
1Central and North West London NHS Foundation Trust, UK.
Abstract:
The COVID-19 pandemic starting in 2020 has had massive mental health consequences worldwide. It has caused generalised fear and anxiety about catching, spreading and suffering from the virus. This article describes a fictionalised patient's presentation of life-threatening obsessive-compulsive disorder (OCD) associated with fears of catching COVID-19. The fears resulted in refusal to eat and drink, with subsequent weight loss that required paediatric admission. The scenario portrays the association between COVID-19 and life-threatening OCD symptoms and goes on to illustrate the patient's good response to standard OCD treatments.
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