Related Experiment Video
Updated: Sep 6, 2025

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
Incidence, Current Guidelines and Management of Gastrointestinal Bleeding after Transcatheter Aortic Valve
Devina Adalja1, Harshvardhan Zala2, Varun Victor3
1Department of Internal Medicine, St Joseph\'s University Medical Center, Paterson, NJ, USA.
Background:
There is a significant increase in morbidity and mortality in patients complicated by major bleeding following transcatheter aortic valve replacement (TAVR). It has become more challenging to manage such complications when the patient needs to be on anticoagulation or antiplatelet agent post-procedure to prevent thrombotic/embolic complications.
Methods:
We systematically reviewed all available randomized controlled trials and observational studies to identify incidence rates of gastrointestinal bleeding post-procedure. After performing a systematic search, a total of 8731 patients from 15 studies (5 RCTs and 10 non-RCTs) were included in this review.
Results:
The average rate of gastrointestinal bleeding during follow-up was 3.0% in randomized controlled trials and 1.9% among observational studies.
Conclusion:
Gastrointestinal bleeding has been noted to be higher in the RCTs as compared to observational studies. This review expands knowledge of current guidelines and possible management of patients undergoing TAVR.
Related Concept Videos
Aneurysm IV: Nursing Management
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Aortic Regurgitation III: Medical Management
Venous Thrombosis III: Interprofessional Care
Venous Thrombosis IV: Nursing Management
Cardiac Catheterization IV: Nursing Management

