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Updated: Jul 29, 2026
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Protocols for Vaginal Inoculation and Sample Collection in the Experimental Mouse Model of Candida vaginitis
Published on: December 8, 2011
Sexual transmission of Candida
Obstetrics and Gynecology
|June 1, 1987
Summary
Recurrent vulvovaginitis in women was linked to fungal reservoirs in oral cavities, rectums, and male ejaculate. Treating these sites and restricting sexual contact cured patients.
Area of Science:
- Mycology
- Gynecology
- Infectious Diseases
Background:
- Chronic recurrent vulvovaginitis significantly impacts women's health.
- Identifying the source of persistent fungal infections is crucial for effective treatment.
Purpose of the Study:
- To investigate potential reservoirs of fungal infection in couples with recurrent vulvovaginitis.
- To determine the correlation between fungal presence in various sites and vaginal infections.
Main Methods:
- Mycotic cultures were obtained from the oral cavity, rectum, vagina, and ejaculate of 33 couples.
- Women in these couples had a diagnosis of chronic recurrent vulvovaginitis.
- Fungal organisms were identified and compared between sites.
Main Results:
- Fungal reservoirs were identified in 36% of oral cavities, 33% of rectums, and 15% of ejaculates.
- The same fungal species were often found in the identified reservoirs and the women's vaginas.
- Male prostatic cultures were consistently negative.
Conclusions:
- Oral cavity, rectum, and ejaculate can serve as significant reservoirs for fungi causing recurrent vulvovaginitis.
- Eliminating fungi from all identified reservoirs and managing sexual contact are key to curing recurrent vulvovaginitis.
- A partner-inclusive approach is essential for managing this condition.
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