Related Experiment Video

Updated: Sep 6, 2025

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
08:42

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Published on: February 11, 2022

3.6K

Mild coronary artery dilatation developed in some children with mild COVID-19 but completely regressed within

Glykeria Rouva1, Eleni Vergadi1, Eleftheria Hatzidaki2

  • 1Department of Pediatrics, University Hospital Heraklion, School of Medicine, University of Crete, Heraklion, Greece.

Acta Paediatrica (Oslo, Norway : 1992)
|June 24, 2022
PubMed

Insights

Mild COVID-19 in children can cause temporary coronary artery dilation, which fully resolves within three months. Further large-scale studies are needed to understand the long-term effects of COVID-19 on pediatric coronary arteries.

Area of Science:

  • Pediatric Cardiology
  • Infectious Diseases
  • Vascular Biology

Background:

  • COVID-19 has been associated with various cardiovascular complications.
  • The impact of mild COVID-19 on coronary arteries in children requires further investigation.

Purpose of the Study:

  • To investigate the incidence and time course of coronary artery changes in children hospitalized with mild COVID-19.
  • To document the prevalence of coronary artery dilation and its regression in pediatric patients.

Main Methods:

  • A single-center prospective study involving 29 children hospitalized for mild COVID-19.
  • Three echocardiographic evaluations were performed at intervals of approximately 19, 82, and 172 days post-symptom onset.
  • Prevalence of coronary artery dilation, regression, and changes was documented using z-scores.

Main Results:

  • Coronary artery dilation was observed in 10.3% of cases at the first evaluation, with complete regression by the second.
  • Complete regression was noted in 75% of cases with follow-up data.
  • Significant z-score changes (>2) were observed in 31% of patients, and 62% showed coronary artery changes at any time point.

Conclusions:

  • Transient and mild coronary artery dilation following mild COVID-19 in children completely regressed within three months.
  • Large-scale studies are necessary to fully elucidate the extent and temporal patterns of coronary artery dilation post-pediatric COVID-19.
Abstract

Keywords:
COVID-19aneurysmcoronary arterydilationpandemic

More Related Videos

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats06:32

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats

Published on: June 28, 2019

8.1K
Myocardial Infarction in Neonatal Mice, A Model of Cardiac Regeneration07:48

Myocardial Infarction in Neonatal Mice, A Model of Cardiac Regeneration

Published on: May 24, 2016

18.8K

Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
21
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
29
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
15
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
30
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
21
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
50