Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Spindle Assembly Checkpoint

The Spindle Assembly Checkpoint

The spindle assembly checkpoint is a molecular surveillance mechanism ensuring the fidelity of chromosome segregation during anaphase. The checkpoint monitors the completion of all the prerequisite steps before chromosome segregation to determine whether the segregation process should proceed or be delayed.
Many proteins function together to control the spindle assembly checkpoint. Mutations affecting these proteins may allow cells to proceed into anaphase prematurely, resulting in the...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Neurodegeneration in Glaucoma: Microstructural Magnetic Resonance Imaging Evidence Within and Beyond the Visual Pathway.

Investigative ophthalmology & visual science·2026

Same author

Nicotinamide Supplementation and Primary Open-Angle Glaucoma in Patients With Ocular Hypertension.

JAMA ophthalmology·2026

Same author

The Metaverse in Ophthalmology: Application and Perceived Benefits, Challenges, Realistic Expectations, and Future Outlook.

Journal of current ophthalmology·2026

Same author

Effect of intraocular pressure control on visual field progression in the HORIZON trial.

Ophthalmology. Glaucoma·2026

Same author

Evaluation of the Deep Reality Viewer for teaching slit-lamp examination of the anterior segment and the optic nerve head.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026

Same author

Comparative Outcomes of Standalone Xen63 Gel Stent and Preserflo Microshunt Implantation: A Multicenter Study.

Clinical ophthalmology (Auckland, N.Z.)·2026

Search research articles

Related Experiment Video

Updated: Sep 6, 2025

Author Spotlight: Unraveling the Molecular Mechanisms in PCO and Fibrosis Following Cataract Surgery

Author Spotlight: Unraveling the Molecular Mechanisms in PCO and Fibrosis Following Cataract Surgery

Published on: December 1, 2023

Deadbolt cataract due to misplanted minishunt.

Richard D Ten Hulzen¹, Isabella V Wagner, Ahmad A Aref

¹Jacksonville, Florida.

Journal of Cataract and Refractive Surgery

|June 24, 2022

Summary

This case discusses managing a patient with glaucoma, a misplaced glaucoma drainage device, and cataracts. It explores counseling on surgical options and visual rehabilitation, focusing on the unique challenges presented by the mispositioned device.

More Related Videos

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice

Published on: November 13, 2016

Using Baseplating and a Miniscope Preanchored with an Objective Lens for Calcium Transient Research in Mice

Using Baseplating and a Miniscope Preanchored with an Objective Lens for Calcium Transient Research in Mice

Published on: June 5, 2021

Related Experiment Videos

Last Updated: Sep 6, 2025

Author Spotlight: Unraveling the Molecular Mechanisms in PCO and Fibrosis Following Cataract Surgery

Author Spotlight: Unraveling the Molecular Mechanisms in PCO and Fibrosis Following Cataract Surgery

Published on: December 1, 2023

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice

Published on: November 13, 2016

Using Baseplating and a Miniscope Preanchored with an Objective Lens for Calcium Transient Research in Mice

Using Baseplating and a Miniscope Preanchored with an Objective Lens for Calcium Transient Research in Mice

Published on: June 5, 2021

Area of Science:

Ophthalmology
Glaucoma Management
Cataract Surgery

Background:

A 62-year-old woman with unilateral glaucoma and a history of complex management, including a steroid response and a trabeculectomy with a glaucoma minishunt, presented for cataract surgery evaluation.
The patient desired refractive cataract surgery to address astigmatism and presbyopia but had concerns about the visual quality and cost of diffractive intraocular lenses (IOLs).

Observation:

The patient presented with nuclear sclerotic and cortical cataracts in both eyes, significant refractive errors, and an epiretinal membrane in the left eye.
A key observation was the misplacement of the glaucoma minishunt in the left eye, with its tip penetrating the peripheral iris and entering the superior capsular bag.

Findings:

Despite the minishunt malposition, intraocular pressure (IOP) was controlled at 10 mm Hg in the left eye without medication.
Visual acuity was 20/40 in both eyes, with significant myopia and astigmatism, and a visual field defect (inferior nasal step) was noted in the left eye.

Implications:

The case highlights the need for careful pre-operative assessment and patient counseling regarding complex glaucoma management and cataract surgery options.
Management strategies must address the mispositioned minishunt, potential risks during cataract surgery, and the selection of appropriate IOLs for visual rehabilitation in a high myope with glaucoma.