Related Experiment Video
Updated: Sep 6, 2025

In Vitro Thrombosis Test for Ventricular Assist Devices
Published on: March 21, 2025
Development and Validation of the Intravenous Infiltration and Extravasation Risk Assessment Tool (IIERAT) for
Sandeep Kaur1, Parvinder Kaur2, Yogesh Kumar1
1Department of Child Health Nursing, Maharishi Markandeshwar College of Nursing, Maharishi Markandeshwar (Deemed to be) University, Mullana, Haryana.
Insights
A new tool, the Intravenous Infiltration and Extravasation Risk Assessment Tool (IIEART), was developed and validated. This tool accurately predicts pediatric patients at risk for intravenous infiltration and extravasation.
Area of Science:
- Pediatric Nursing
- Patient Safety
- Clinical Tool Development
Background:
- Intravenous (IV) fluid extravasation is a common complication in pediatric patients.
- Early identification of risk is crucial for preventing adverse events.
- Existing tools may lack specificity or validation in pediatric populations.
Purpose of the Study:
- To develop and validate the Intravenous Infiltration and Extravasation Risk Assessment Tool (IIEART).
- To provide a reliable method for assessing extravasation risk in children undergoing peripheral IV cannulation.
Main Methods:
- The IIEART was developed through a four-phase process including Modified Delphi rounds with nine experts.
- Psychometric properties were determined using data from 120 children (aged 2-18 years).
- Reliability (internal consistency, inter-rater) and validity (predictive) were assessed.
Main Results:
- The final 11-item IIEART demonstrated good internal consistency (α=0.81) and excellent inter-rater reliability (κ=0.88).
- Predictive validity showed 100% sensitivity and 100% specificity at a score >21 on the second day post-cannulation.
- Area under the curve was 1.0, indicating high diagnostic accuracy.
Conclusions:
- The IIEART is a valid and reliable tool for healthcare professionals.
- It can effectively predict pediatric patients at risk of IV infiltration and extravasation.
- Implementation of IIEART can enhance patient safety and reduce complications.
Objective:
To develop and validate a new tool viz., Intravenous Infiltration and Extravasation Risk Assessment Tool (IIEART) for assessing risk of fluid extravasation in children.
Participants:
120 children (aged 2-18 year) undergoing peripheral intravenous cannulation were recruited from four hospitals of Haryana to determine the IIEART scale's psychometric properties.
Methods:
The tool was developed under four phases with Modified Delphi rounds among nine experts. After experts' confirmation of final draft, the reliability and validity of the tool was ascertained.
Results:
The final IIERAT with 11 items showed good internal consistency (a=0.81) with inter-rater reliability of (k=0.88). To calculate predictive validity, sensitivity and specificity were assessed for 3 consecutive days from the day of cannulation. At a score >21, the sensitivity was 100% and specificity was 100% with area under curve of 1.0 (95% CI 1.0, 1.0) on second day of cannulation.
Conclusion:
The IIEART developed was found to be valid and reliable and can be used by healthcare personnel to predict pediatric patients at risk for intravenous infiltration and extravasation.
Related Concept Videos
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Acute Kidney Injury V: Interprofessional Care
One-Compartment Open Model for IV Bolus Administration: Estimation of Clearance
In the one-compartment open model for intravenous (IV) bolus administration, clearance is estimated by dividing the elimination rate by the plasma drug concentration. This equation leverages the elimination rate constant and the apparent...

