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Updated: Sep 6, 2025

A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo
Published on: August 28, 2014
Strategies for Regenerative Vascular Tissue Engineering
Yao Wang1,2, Mozhgan Keshavarz1,2, Patrick Barhouse1,2
1Department of Chemical and Biomolecular Engineering, University of California, Irvine, CA, 92697, USA.
Abstract:
Vascularization remains one of the key challenges in creating functional tissue-engineered constructs for therapeutic applications. This review aims to provide a developmental lens on the necessity of blood vessels in defining tissue function while exploring stem cells as a suitable source for vascular tissue engineering applications. The intersections of stem cell biology, material science, and engineering are explored as potential solutions for directing vascular assembly.

