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Correlation between overactive bladder and detrusor overactivity: a retrospective study.

Ting-Xuan Huang1, Tsia-Shu Lo2,3,4,5, Hsiao-Jung Tseng6

  • 1Division of Urogynecology, Department of Obstetrics and Gynecology, Linkou, Chang Gung Memorial Hospital, Linkou Medical Center, 5, Fu-Hsin Street, Kwei-shan, Tao-Yuan City, Taiwan, 333, Republic of China.

International Urogynecology Journal
|June 25, 2022
PubMed
Summary
This summary is machine-generated.

Overactive bladder (OAB) affects 36.4% of women with lower urinary tract symptoms (LUTS). Detrusor overactivity (DO) is linked to older age, parity, and poorer bladder function, suggesting combined assessments improve OAB diagnosis.

Keywords:
Detrusor overactivityOveractive bladderPredictive modelUrodynamic studyValidated questionnaire

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Area of Science:

  • Urology
  • Gynecology
  • Female Lower Urinary Tract Symptoms

Background:

  • Overactive bladder (OAB) and detrusor overactivity (DO) are common conditions affecting women with lower urinary tract symptoms (LUTS).
  • Urodynamic study (UDS) is a key diagnostic tool for evaluating these conditions.
  • Understanding the prevalence and characteristics of OAB and DO is crucial for effective patient management.

Purpose of the Study:

  • To determine the prevalence of OAB and DO in female patients referred for UDS due to LUTS.
  • To compare subjective and objective differences between female OAB patients with and without DO.

Main Methods:

  • Retrospective review of 1524 female patients undergoing UDS for LUTS between June 2016 and September 2019.
  • Collection of personal/medical history, physical examination, and validated questionnaires.
  • Performance of one-hour pad test and multichannel urodynamic study.

Main Results:

  • OAB prevalence was 36.4%; DO incidence in OAB patients was 15.5%.
  • Patients with DO were older, had higher parity, experienced more urine leakage, and showed worse UDS storage/micturition function.
  • Significant differences were observed in OAB symptom scores, quality of life measures, and UDS parameters between patients with and without DO.

Conclusions:

  • DO is associated with older age, increased parity, greater urine leakage, and impaired bladder function.
  • Combined subjective and objective measurements provide better predictive models for diagnosing OAB patients.