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Updated: Sep 6, 2025

Reducing State Anxiety Using Working Memory Maintenance
Published on: July 19, 2017
State and Trait Anxiety Related Gamma Oscillations in Patients With Anxiety Within the Research Domain Criteria
Kyoung Min Kim1, Su Hyun Bong2, Jun Byeon2
1Department of Psychiatry, Dankook University College of Medicine, Cheonan, Republic of Korea.
Objective:
Diagnosis of anxiety has relied primarily on self-report. This study aimed to investigate the neural correlates of anxiety with quantitative electroencephalography (qEEG) focusing on the state and trait anxiety defined according to the Research Domain Criteria framework existing across the differential diagnosis, rather than focusing on the diagnosis.
Methods:
A total of 41 participants who visited a psychiatric clinic underwent resting state EEG and completed the State-Trait Anxiety Inventory. The absolute power of six frequency bands were analyzed: delta (1-4 Hz), theta (4-8 Hz), alpha (8-10 Hz), fast alpha (10-13.5 Hz), beta (13.5-30 Hz), and gamma (30-80 Hz).
Results:
State anxiety scores were significantly negatively correlated with absolute gamma power in frontal (Fz, r=-0.484) and central (Cz, r=-0.523) regions, while trait anxiety scores were significantly negatively correlated with absolute gamma power in frontal (Fz, r= -0.523), central (Cz, r=-0.568), parietal (P7, r=-0.500; P8, r=-0.541), and occipital (O1, r=-0.510; O2, r=-0.480) regions.
Conclusion:
The present study identified the significantly negative correlations between the anxiety level and gamma band power in fronto-central and posterior regions assessed at resting status. Further studies to confirm our findings and identify the neural correlates of anxiety are needed.
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