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Updated: Jul 18, 2026
Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice
Published on: August 4, 2011
[Retinoblastoma at the Campus-University Teaching Hospital in Lomé, Togo, from 2014 to 2018]
B M Diatewa1, N Maneh2, A S Domingo1
1Service d'ophtalmologie, CHU - Campus de Lomé, Lomé, Togo.
Introduction:
Retinoblastoma is a curable cancer when management is early and prompt.
Objective:
To describe the epidemiological, clinical and therapeutic aspects of retinoblastoma.
Materials And Methods:
A retrospective study was carried out from January 2014 to December 2018 (5 years) at the department of ophthalmology in Campus-University Teaching Hospital, Lomé, Togo. It focused on children with retinoblastoma. It included patients with diagnosis supported by ocular ultrasonography, orbito-cerebral computed tomography scan and/or histopathological examination.
Results:
Among the 75 children with ocular cancer, 26 (34.7%) were diagnosed with retinoblastoma. The mean age at presentation was 31 months. The mean time from symptom onset to diagnosis was 15 months. A predominance of proptosis (65.4%), unilateral involvement (76.9%), extraocular tumor extension (65.4%) and endophytic form (96.15%) was found. Of the 32 eyes with retinoblastoma, 7 (21.9%) were enucleated after a mean time from diagnosis to enucleation of 6 months. Two cases of complete remission, 3 cases of tumor recurrence, and 2 cases lost to follow-up were noted.
Conclusion:
In our setting, retinoblastoma is a frequent childhood ocular cancer. It is important to improve the management of retinoblastoma as well as education of the parents.
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