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Updated: Sep 6, 2025

An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney
Published on: November 1, 2018
An unusually "complex" glomerulonephritis
Gabriela Martinez-Zayas1, Daniel Savino2, Sumit Kumar3
1Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas.
Abstract:
A 53-year-old man with granulomatosis with polyangiitis presented with fever and acute kidney injury with nephrotic-range proteinuria following the second dose of the mRNA COVID-19 vaccine. Renal biopsy revealed an unexpected immune complex-glomerulonephritis (IC-GN) without vasculitis. Further workup found the patient to have HIV that was unmasked following the treatment of IC-GN. This case report explores the possible relationship between COVID-19 vaccines and the immune response in the setting of chronic HIV.
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