Related Experiment Video
Updated: Sep 6, 2025
08:53
Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
Published on: December 4, 2020
6.3K
Aerococcus urinae tricuspid valve infective endocarditis
Sanchari Banerjee1, Sindhubarathi Murali1, Atika Azhar1
1Department of Internal Medicine, State University of New York Upstate Medical University, Syracuse, New York.
Proceedings (Baylor University. Medical Center)
|June 27, 2022
Summary
Aerococcus urinae, a cause of urinary tract infections, can lead to infective endocarditis, particularly affecting heart valves. This case highlights successful treatment of A. urinae endocarditis with penicillin G.
Area of Science:
- Microbiology
- Infectious Diseases
- Cardiology
Background:
- Aerococcus urinae is an alpha-hemolytic, gram-positive coccus causing urinary tract infections (UTIs).
- Risk factors for A. urinae UTIs include male gender, advanced age, and genitourinary abnormalities.
- A. urinae is often misidentified as Staphylococcus or Streptococcus due to similar morphology.
Observation:
- Fewer than 50 cases of A. urinae infective endocarditis have been reported, typically involving the mitral or aortic valve.
- This report details a 61-year-old woman with A. urinae bacteremia presenting with recurrent fevers and dyspnea.
- Transesophageal echocardiogram revealed moderate tricuspid valve regurgitation and vegetations on the posterior and septal leaflets.
Findings:
- The patient was diagnosed with A. urinae bacteremia and tricuspid valve endocarditis.
- Successful treatment was achieved with a 6-week course of intravenous penicillin G.
- The patient was not a candidate for cardiac surgery.
Implications:
- This case expands the understanding of A. urinae as a pathogen in infective endocarditis, specifically involving the tricuspid valve.
- It underscores the importance of accurate identification of A. urinae to guide appropriate treatment.
- The successful non-surgical management highlights a potential therapeutic approach for select cases of A. urinae endocarditis.
Related Concept Videos
01:25Endocarditis I: Introduction
25
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
25
01:25Endocarditis II: Clinical Features of Infective Endocarditis
23
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
23
01:18Endocarditis III: Medical Management
15
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
15
01:25Urinary Tract Infection II: Pathophysiology
43
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
43
01:29Endocarditis IV: Nursing Management
26
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
26
01:26Urinary Tract Infection I: Introduction
44
Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
44